Avinza 120mg Capsule

Understanding Avinza (Morphine Sulfate) 120mg Capsule: A Comprehensive Overview

Avinza 120mg Capsule, is a prescription medication containing morphine sulfate, an opioid analgesic use to manage moderate to severe pain that requires continuous, around-the-clock treatment. The 120mg extend-release (ER) capsule formulation is design for once-daily administration, offering a consistent release of morphine to provide prolong pain relief.

Indications and Usage

Avinza 120mg Capsule, is indicate for the relief of moderate to severe pain in patients who require continuous, around-the-clock opioid therapy for an extend period. It is not intend for use as a prn (as-need) analgesic or for mild pain. The 120mg dose is specifically for patients who are opioid-tolerant, meaning they have been receiving, for one week or longer, at least 60 mg oral morphine per day, 25 mcg transdermal fentanyl per hour, 30 mg oral oxycodone per day, or an equianalgesic dose of another opioid.

Dosage and Administration

Avinza capsules should be swallow whole. If a patient has difficulty swallowing capsules, the contents can be sprinkle on applesauce and swallow immediately without chewing. The capsules must not be crush, chew, or dissolve, as this can lead to the rapid release and absorption of a potentially fatal dose of morphine.

Mechanism of Action

Morphine sulfate, the active ingredient in Avinza, is an opioid analgesic that works by binding to specific receptors in the brain and spinal cord, known as opioid receptors. This binding alters the perception of and response to pain, providing relief. The extended-release formulation ensures a gradual release of morphine over a 24-hour period, maintaining consistent pain control.

Side Effects

Common side effects of Avinza may include:

• Constipation

• Drowsiness

• Dizziness

• Nausea and vomiting

• Sweating

• Dry mouth

Serious side effects can occur and may include respiratory depression, hypotension, seizures, and addiction. Patients should be monitored for signs of misuse, abuse, and addiction. The risk of overdose and death is increased if Avinza is misused or abused.

Precautions and Contraindications

Avinza is contraindicated in patients with:

• Severe respiratory depression

• Acute or severe bronchial asthma

• Known or suspected gastrointestinal obstruction

• Hypersensitivity to morphine